S1R agonist 2

CAS No. 150085-21-5

S1R agonist 2( —— )

Catalog No. M36422 CAS No. 150085-21-5

S1R agonist 2 is a selective S1R agonist with a Ki of 88 nM for S2R and 1.1 nM for S1R and is protective against ROS and NMDA-induced neurotoxicity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 59 Get Quote
5MG 88 Get Quote
10MG 141 Get Quote
25MG 264 Get Quote
50MG 400 Get Quote
100MG 579 Get Quote
500MG 1224 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    S1R agonist 2
  • Note
    Research use only, not for human use.
  • Brief Description
    S1R agonist 2 is a selective S1R agonist with a Ki of 88 nM for S2R and 1.1 nM for S1R and is protective against ROS and NMDA-induced neurotoxicity.
  • Description
    S1R agonist 2 (Compound 8b) is a selective S1R agonist with Kis of 1.1 nM and 88 nM for S1R and S2R, respectively. S1R agonist 2 exhibits neuroprotection against ROS and NMDA-induced neurotoxicity.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Autophagy
  • Target
    Sigma receptor
  • Recptor
    Sigma receptor | ROS | NMDAR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    150085-21-5
  • Formula Weight
    309.45
  • Molecular Formula
    C21H27NO
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C(C1CCN(CCCOC2=CC=CC=C2)CC1)C3=CC=CC=C3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Linciano P, et al. Novel S1R agonists counteracting NMDA excitotoxicity and oxidative stress: A step forward in the discovery of neuroprotective agents. Eur J Med Chem. 2023 Mar 5;249:115163.?
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